Daniel Estève is research director at CEA-Saclay where he is in charge of the Quantronique team of the Condensed State Physics Department. He is a member of the French Academy of Sciences and contributed to the creation of the European Research Council where he was vice-president of the scientific council for two terms (2006-2011). After a thesis in Nuclear Magnetic Resonance in the laboratory of  Professor A. Abragam's laboratory on orientation problems in molecular solids (1982), he turned his attention to nascent mesoscopic physics and created with M. Devoret and C. Urbina the Quantronique group to design, realize and measure electrical circuits in which quantum physics is manifested at the level of the electrical variables of the circuit. These include the effect of dissipation on the macroscopic quantum tunnelling effect in a Josephson junction, electrical transport in single atom contacts, the electron pump where the electrical current is controlled electron by electron, and the Cooper pair box which is at the origin of the superconducting quantum bit circuits currently in use. The demonstration in the early 2000s of such a circuit functional enough to reproduce the founding experiments of quantum mechanics provided an electrical basis for the nascent quantum computing. The two-bit quantum elementary processor realized in the early 2010's brought a first demonstration with an electric circuit of the quantum acceleration of Grover's quantum search algorithm.  Since then, the Quantronique group has moved towards the search for quantum bits with better quantum coherence based on individual spins controlled by quantum electrical circuits, which has led for the moment to improve the sensitivity of the electronic paramagnetic resonance by several orders of magnitude.  Daniel Estève has also contributed to the development of mesoscopic superconductivity and microwave quantum optics. He has co-supervised about 20 PhD students and as many post-doctoral fellows and has authored or co-authored more than 200 publications with 13000 citations. He has been awarded several national and international scientific prizes.